Model family

ether0

ether0 is a model family from FutureHouse1 3 4, with 1 assessed release in this catalog. Licenses and availability are recorded for each release, not for the family; its releases use the Apache License 2.0.

ether0 is a 24B-parameter chemistry reasoning model from FutureHouse, released in June 2025. It reasons in English and answers with molecular structures written as SMILES. It was fine-tuned and trained with reinforcement learning from Mistral AI's Mistral-Small-24B-Instruct-2501.1 4 2Fact reviewed Oct 1, 2026

Last reviewedOct 1, 2026Entry updated Oct 1, 2026Documented release Jun 2025

Releases assessed

Each release is assessed on its own. This family has no family-wide openness label.

Releases in the ether0 family
Release	Weights	Tier (USASI rubric v0.2)	License	Released
ether0 (24B)	Weights: Public	Model-disclosure tier (USASI rubric v0.2): Open-weight	Apache-2.0, Apache-2.0	Jun 4, 2025

What it is useful for

The model card lists molecule-design and prediction tasks it was trained for, including IUPAC name or formula to SMILES, adjusting solubility, pKa, or scent, ADME and toxicity properties, one-step retrosynthesis, reaction outcome prediction, and molecule captioning in reverse. The card says it is not a general-purpose chat model.1Fact reviewed Oct 1, 2026

Organization context

FutureHouse

U.S. eligibility

Project eligibility rests on documented governing or maintaining entities, not on contributors.

Eligible · basis: U.S.-governed project

ether0 is published by FutureHouse on its Hugging Face and GitHub organizations, and the model card states a 2025 FutureHouse copyright. FutureHouse is a 501(c)(3) nonprofit in San Francisco per its about page and the IRS exempt-organization extract. The base model, Mistral-Small-24B-Instruct-2501, comes from Mistral AI and is recorded as provenance on the release record, not as a U.S. model.1 3 5 6

Assessed Oct 1, 2026

Sources

1.
futurehouse/ether0 model card (external site: huggingface.co)
FutureHouse · Model card · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026
2.
futurehouse/ether0 (Hugging Face model API metadata) (external site: huggingface.co)
Hugging Face · Other · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026
3.
Future-House/ether0 README (external site: raw.githubusercontent.com)
FutureHouse · Repository · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026
4.
ether0: a scientific reasoning model for chemistry (external site: futurehouse.org)
FutureHouse · Announcement · published Jun 5, 2025 · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026
5.
About | FutureHouse (external site: futurehouse.org)
FutureHouse · Official page · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026
6.
Exempt Organizations Business Master File Extract - California (eo_ca.csv) (external site: irs.gov)
Internal Revenue Service · Filing · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

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This listing is not an endorsement, a safety assessment, or a federal approval.

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APA style

USASI. (2026, October 1). ether0. United States of America Superintelligence. https://unitedstatesofamericasuperintelligence.com/open/ether0/

BibTeX

@misc{usasi_ether0,
  author = {{USASI}},
  title = {ether0},
  year = {2026},
  month = oct,
  howpublished = {\url{https://unitedstatesofamericasuperintelligence.com/open/ether0/}},
  note = {United States of America Superintelligence. Last updated 2026-10-01}
}

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Releases assessed

What it is useful for

Organization context

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