USASI
Model release

Evo 2 20B

Release in the Evo 2 family · version evo2_20b

Maintained by Arc Institute14

A 20-billion-parameter Evo 2 checkpoint with 1 million base-pair context, released in February 2026. Arc created it from Evo 2 40B without additional training by removing layers that logit-lens analysis showed could be dropped with little effect on loss, while keeping the unembedding layer.14

Last reviewedEntry updated Documented release Feb 28, 2026

Availability and license

Overall availability

Public

Downloadable from Hugging Face without gating.12

Availability is separate from permission: read the license before using or redistributing.

The evo2 LICENSE file also carries the notices for bundled third-party code, including a BSD-style NVIDIA license and the MIT license for Fairseq code.6

Model-disclosure tier

Computed from the checklist below using USASI rubric v0.1. An editorial category, not a certification.
Model-disclosure tier (USASI rubric v0.1): Open-weight

The model parameters for this release can be downloaded by the public. License terms may still restrict use, redistribution, or commercial use.

How tiers are computed

Public materials checklist

Items for a model under USASI rubric v0.1. Unknown means unassessed or insufficient evidence.
Public materials checklist for Evo 2 20B
ItemStatusNotes and evidence
WeightsCan the general public download the model parameters for this release?PublicWeights are on Hugging Face without gating; a Savanna-format checkpoint (savanna_evo2_20b) is also published.123
Inference codeIs code for running the model published?PublicThe evo2 package on GitHub supports evo2_20b under Apache 2.0.56
Training codeIs the code used to train the model published?PartialNo further training was done; the weights come from Evo 2 40B, which the README says was trained with the open-source Savanna framework. Code for the layer-removal step was not identified.45
Training-data informationPublic = the training data itself can be obtained. Partial = composition or sources are documented without full access.PublicThe card lists OpenGenome2, the Evo 2 pretraining dataset, which is downloadable from Hugging Face.17
Training recipeAre the training configuration and procedure documented in enough detail to follow?PartialThe release notes describe the layer-removal method at a high level; the exact layers removed were not found in the pages reviewed.4
Evaluation materialsPublic = evaluation code or prompts that let others re-run the evaluations are published. Partial = results only.PartialThe release notes compare the 20B and 40B checkpoints on variant effect prediction and gene completion; evaluation scripts for those comparisons were not identified.4

What it is useful for

The same tasks as Evo 2 40B (likelihood scoring, embeddings, and generation of DNA sequences) on less hardware; the release notes describe it as running on a single H100 GPU instead of two.45

Run and use notes

Documented facts only. No hardware or performance claims are made without a cited source and stated assumptions.
  • The README states that evo2_20b needs FP8 through NVIDIA Transformer Engine and an NVIDIA Hopper GPU for numerical accuracy; the release notes say it runs on a single H100.54

Organization context

Provenance and derivatives

Derived by Arc Institute from its own Evo 2 40B checkpoint through layer removal, without additional training.4

Other releases in the Evo 2 family

  • Evo 2 40BModel-disclosure tier (USASI rubric v0.1): Open-stack

Evo 2 family overview

U.S. eligibility

Project eligibility rests on documented governing or maintaining entities, not on contributors.

Eligible · basis: U.S.-governed project

The checkpoint is published in Arc Institute's Hugging Face organization and announced in Arc's GitHub release notes. Arc Institute is a Palo Alto, California nonprofit research organization listed by the IRS as a 501(c)(3).1489

Assessed Sep 29, 2026

Sources

  1. 1.
    arcinstitute/evo2_20b model card (external site: huggingface.co)

    Arc Institute · Model card · accessed Sep 29, 2026

  2. 2.
  3. 3.
  4. 4.
    Release v0.5.0 · ArcInstitute/evo2 (external site: github.com)

    Arc Institute · Release notes · published Feb 28, 2026 · accessed Sep 29, 2026

  5. 5.
    ArcInstitute/evo2 README (external site: github.com)

    Arc Institute · Repository · accessed Sep 29, 2026

  6. 6.
    ArcInstitute/evo2 LICENSE (external site: raw.githubusercontent.com)

    Arc Institute · License · accessed Sep 29, 2026

  7. 7.
    arcinstitute/opengenome2 dataset card (external site: huggingface.co)

    Arc Institute · Dataset card · accessed Sep 29, 2026

  8. 8.
    About | Arc Institute (external site: arcinstitute.org)

    Arc Institute · Official page · accessed Sep 29, 2026

  9. 9.

This listing is not an endorsement, a safety assessment, or a federal approval.

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