USASI

Organization

Arc Institute

Research lab · Nonprofit research · Model developer · Palo Alto, California

Arc Institute is an independent nonprofit research organization in Palo Alto, California, founded in 2021, that works in partnership with Stanford University, UC Berkeley, and UCSF. Its research spans experimental biology and computational models, including the Evo 2 DNA language model and virtual cell models.134

Last reviewedEntry updated

Key facts

Legal name
Arc Research Institute82
Ownership
Nonprofit
Legal form
Corporation recognized by the IRS as tax-exempt under Section 501(c)(3); the IRS extract classifies it as a hospital or medical research organization (170(b)(1)(A)(iii)).89
Headquarters
Palo Alto, California12
Founded
20211
Sectors
Science, Research, Open models

What is and isn’t public

An evidence-based summary of what this catalog has documented. It is not a verdict on the organization as a whole.

Evo 2 model weights, inference code, and training data are published under Apache 2.0 (see the Evo 2 records). This catalog assesses openness release by release, not for Arc as a whole.576

Products

Documented products and how they are delivered. Each row links to the official page.

No product records yet.

Related open artifacts

Records in the Open Models & Tools directory that list this organization as a maintainer or publisher.

Model families (1)

Model releases (2)

  • Evo 2 20BModel releaseAvailability: PublicModel-disclosure tier (USASI rubric v0.1): Open-weight
  • Evo 2 40BModel releaseAvailability: PublicModel-disclosure tier (USASI rubric v0.1): Open-stack

Notable documented facts

  • Arc describes Evo 2 as developed by Arc and NVIDIA scientists together with collaborators at Stanford University, UCSF, UC Berkeley, Goodfire, and the University of Washington. It was released as a preprint in February 2025 and published in Nature on March 4, 2026.4
  • Arc publishes Evo 2 code on GitHub and Evo 2 checkpoints and the OpenGenome2 training dataset on Hugging Face under the Apache License 2.0.576

U.S. eligibility

How this record meets the catalog’s published eligibility policy.

Eligible · basis: U.S. nonprofit or lab

Arc Institute describes itself as an independent nonprofit research organization based in Palo Alto, California, and its contact page gives a Palo Alto address. The IRS exempt-organization extract for California lists Arc Research Institute at that address as a 501(c)(3) organization.128

Assessed Sep 29, 2026

Eligibility policy

Sources

  1. 1.
    About | Arc Institute (external site: arcinstitute.org)

    Arc Institute · Official page · accessed Sep 29, 2026

  2. 2.
    Contact | Arc Institute (external site: arcinstitute.org)

    Arc Institute · Official page · accessed Sep 29, 2026

  3. 3.
    Evo 2: DNA Foundation Model | Arc Institute (external site: arcinstitute.org)

    Arc Institute · Official page · accessed Sep 29, 2026

  4. 4.
    Evo 2: One Year Later (external site: arcinstitute.org)

    Arc Institute · Announcement · published Mar 4, 2026 · accessed Sep 29, 2026

  5. 5.
    ArcInstitute/evo2 (external site: github.com)

    Arc Institute · Repository · accessed Sep 29, 2026

  6. 6.
    arcinstitute/opengenome2 dataset card (external site: huggingface.co)

    Arc Institute · Dataset card · accessed Sep 29, 2026

  7. 7.
  8. 8.
  9. 9.
    Exempt Organization Business Master File Extract information sheet (external site: irs.gov)

    Internal Revenue Service · Documentation · published Jan 2026 · accessed Sep 29, 2026

This listing is not an endorsement or a federal approval.

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